PeptidePicker
Get Started
Home/Peptides/MK-677
Growth HormoneResearch

MK-677

Also known as: Ibutamoren · MK677

An oral, non-peptide growth hormone secretagogue that elevates GH and IGF-1 levels for up to 24 hours. Popular for its convenience and effects on sleep, bone density, and body composition.

Dr. Sarah Mitchell

Reviewed by Dr. Sarah Mitchell, PharmD, BCPS

Lead Researcher · 12+ years in peptide therapeutics

Half-Life

~5 hours (IGF-1 elevation ~24h)

Typical Dose

10–25 mg daily

Administration

Oral

Mechanism of Action

Mimics ghrelin at the GHS-R1a receptor to stimulate continuous pituitary GH release without suppressing natural production.

Key Research Areas

growth hormoneoralIGF-1sleepmuscle

Frequently Asked Questions

What is MK-677?▾
An oral, non-peptide growth hormone secretagogue that elevates GH and IGF-1 levels for up to 24 hours. Popular for its convenience and effects on sleep, bone density, and body composition.
How does MK-677 work?▾
Mimics ghrelin at the GHS-R1a receptor to stimulate continuous pituitary GH release without suppressing natural production.
What is the recommended dosage for MK-677?▾
The typical research dosage is 10–25 mg daily, administered via Oral. Dosage protocols vary by study and should be determined by a qualified healthcare professional.
What is the half-life of MK-677?▾
The half-life of MK-677 is approximately ~5 hours (IGF-1 elevation ~24h). This affects dosing frequency and timing in research protocols.
Is MK-677 FDA approved?▾
MK-677 is currently classified as "Research" and is not FDA approved for general use. It is available for research purposes or through compounding pharmacies depending on your jurisdiction.

Research Disclaimer

The information provided about MK-677 is for educational purposes only and is not intended as medical advice. Always consult a qualified healthcare professional before starting any peptide protocol. Products discussed have not been evaluated by the FDA unless explicitly noted.

Related Peptides in Growth Hormone

Sermorelin

GRF 1-29 · Geref

Ipamorelin

NNC 26-0161

CJC-1295

Mod GRF(1-29) · Modified GRF

Tesamorelin

Egrifta

Back to All PeptidesFind Your Peptide — Take the Quiz