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Melanotan II

Also known as: MT-2 · Melanotan 2

A potent alpha-MSH analog that stimulates melanogenesis for deep skin pigmentation with minimal UV exposure. Also known for side effects including appetite suppression and sexual arousal.

Dr. Sarah Mitchell

Reviewed by Dr. Sarah Mitchell, PharmD, BCPS

Lead Researcher · 12+ years in peptide therapeutics

Half-Life

~1 hour

Typical Dose

0.25–0.5 mg

Administration

Subcutaneous injection

Mechanism of Action

Broadly activates melanocortin receptors (MC1R–MC5R) to stimulate melanocyte activity, increase eumelanin production, and modulate appetite and sexual function.

Key Research Areas

tanningmelanocortinpigmentationappetitesexual

Frequently Asked Questions

What is Melanotan II?
A potent alpha-MSH analog that stimulates melanogenesis for deep skin pigmentation with minimal UV exposure. Also known for side effects including appetite suppression and sexual arousal.
How does Melanotan II work?
Broadly activates melanocortin receptors (MC1R–MC5R) to stimulate melanocyte activity, increase eumelanin production, and modulate appetite and sexual function.
What is the recommended dosage for Melanotan II?
The typical research dosage is 0.25–0.5 mg, administered via Subcutaneous injection. Dosage protocols vary by study and should be determined by a qualified healthcare professional.
What is the half-life of Melanotan II?
The half-life of Melanotan II is approximately ~1 hour. This affects dosing frequency and timing in research protocols.
Is Melanotan II FDA approved?
Melanotan II is currently classified as "Research" and is not FDA approved for general use. It is available for research purposes or through compounding pharmacies depending on your jurisdiction.

Research Disclaimer

The information provided about Melanotan II is for educational purposes only and is not intended as medical advice. Always consult a qualified healthcare professional before starting any peptide protocol. Products discussed have not been evaluated by the FDA unless explicitly noted.

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