Comparison
Selank vs Semax
Russia's two premier nootropic peptides compared.
Reviewed by Dr. Sarah Mitchell, PharmD
Primary Effect
Anxiolytic (anxiety reduction)
Stimulatory (focus/energy)
Derived From
Tuftsin (immunopeptide)
ACTH fragment (stress hormone)
Best For
Anxiety, calm focus, mood
Concentration, productivity, memory
Administration
Intranasal
Intranasal
Half-Life
~3 minutes
~2–3 minutes
Addiction Risk
None
None
BDNF Effect
Moderate increase
Strong increase
Stackable?
Yes — with Semax
Yes — with Selank
Our Verdict
Selank is primarily anxiolytic (anxiety-reducing) with secondary cognitive benefits. Semax is primarily stimulatory (focus and energy) with secondary neuroprotective effects. They can be stacked. Choose Selank for calm focus, Semax for intense productivity.