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AntimicrobialResearch

Alpha-Defensin 1

Also known as: HNP-1 · DEFA1

An endogenous antimicrobial peptide from human neutrophils that shreds bacterial membranes and bridges innate-to-adaptive immune memory.

Dr. Sarah Mitchell

Reviewed by Dr. Sarah Mitchell, PharmD, BCPS

Lead Researcher · 12+ years in peptide therapeutics

Half-Life

~2–4 hours

Typical Dose

Research dosing

Administration

Research

Mechanism of Action

Forms pores in microbial membranes through voltage-dependent channels while simultaneously activating dendritic cells for adaptive immunity.

Key Research Areas

antimicrobialimmuneneutrophilinnate defense

Frequently Asked Questions

What is Alpha-Defensin 1?▾
An endogenous antimicrobial peptide from human neutrophils that shreds bacterial membranes and bridges innate-to-adaptive immune memory.
How does Alpha-Defensin 1 work?▾
Forms pores in microbial membranes through voltage-dependent channels while simultaneously activating dendritic cells for adaptive immunity.
What is the recommended dosage for Alpha-Defensin 1?▾
The typical research dosage is Research dosing, administered via Research. Dosage protocols vary by study and should be determined by a qualified healthcare professional.
What is the half-life of Alpha-Defensin 1?▾
The half-life of Alpha-Defensin 1 is approximately ~2–4 hours. This affects dosing frequency and timing in research protocols.
Is Alpha-Defensin 1 FDA approved?▾
Alpha-Defensin 1 is currently classified as "Research" and is not FDA approved for general use. It is available for research purposes or through compounding pharmacies depending on your jurisdiction.

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Research Disclaimer

The information provided about Alpha-Defensin 1 is for educational purposes only and is not intended as medical advice. Always consult a qualified healthcare professional before starting any peptide protocol. Products discussed have not been evaluated by the FDA unless explicitly noted.

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