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MitochondrialResearch

AICAR

Also known as: Acadesine

An AMPK activator studied for endurance enhancement and metabolic effects. Sometimes called an exercise-in-a-pill compound.

Dr. Sarah Mitchell

Reviewed by Dr. Sarah Mitchell, PharmD, BCPS

Lead Researcher · 12+ years in peptide therapeutics

Half-Life

~2–3 hours

Typical Dose

Research dosing

Administration

Subcutaneous injection

Mechanism of Action

Directly activates AMP-activated protein kinase, shifting metabolism toward fat oxidation and mimicking the metabolic effects of exercise.

Key Research Areas

AMPKenduranceexercise mimeticmetabolism

Frequently Asked Questions

What is AICAR?▾
An AMPK activator studied for endurance enhancement and metabolic effects. Sometimes called an exercise-in-a-pill compound.
How does AICAR work?▾
Directly activates AMP-activated protein kinase, shifting metabolism toward fat oxidation and mimicking the metabolic effects of exercise.
What is the recommended dosage for AICAR?▾
The typical research dosage is Research dosing, administered via Subcutaneous injection. Dosage protocols vary by study and should be determined by a qualified healthcare professional.
What is the half-life of AICAR?▾
The half-life of AICAR is approximately ~2–3 hours. This affects dosing frequency and timing in research protocols.
Is AICAR FDA approved?▾
AICAR is currently classified as "Research" and is not FDA approved for general use. It is available for research purposes or through compounding pharmacies depending on your jurisdiction.

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Research Disclaimer

The information provided about AICAR is for educational purposes only and is not intended as medical advice. Always consult a qualified healthcare professional before starting any peptide protocol. Products discussed have not been evaluated by the FDA unless explicitly noted.

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